Epithalon (also known as Epitalon or Epithalone) is a small synthetic tetrapeptide with the amino acid sequence Ala‑Glu‑Asp‑Gly. It is derived from a natural peptide produced in the pineal gland and is researched for its potential effects on cellular aging, telomere regulation, and longevity‑related mechanisms in laboratory settings. In scientific studies, Epithalon is often investigated for its ability to activate telomerase, influence gene expression related to aging, and support cellular maintenance pathways.

Epithalon is typically supplied as a white to off‑white lyophilized (freeze‑dried) powder for research use. Before use in experiments, the peptide must be reconstituted with an appropriate sterile solvent, such as sterile water or bacteriostatic water. The peptide’s purity is generally ≥ 98%, verified through analytical methods such as High‑Performance Liquid Chromatography (HPLC) or Mass Spectrometry (MS) to ensure consistency and reliability in research applications.

For storage, Epithalon should be kept in a cool, dry place. For long‑term stability, the unopened lyophilized powder is usually stored at ‑20°C or lower. After reconstitution, the peptide solution should be stored in the refrigerator (2°C to 8°C) and used within the timeframe recommended by the supplier. It is important to avoid repeated freeze/thaw cycles, as these can degrade the peptide and reduce its effectiveness in research protocols.

A Certificate of Analysis (COA) is typically provided with each batch of Epithalon. The COA confirms key quality metrics, such as purity percentage, peptide identity, molecular weight verification, and recommended storage conditions, as well as the batch/lot number for traceability. Epithalon is intended strictly for laboratory research purposes and is not FDA‑approved for clinical use, human consumption, or therapeutic applications. It is most commonly used in research exploring telomere biology, cellular aging, and longevity mechanisms at the molecular and cellular levels.